| Average cholestrol reduction (percent) | Average LDL reduction (percent) | Average HDL increase (percent) | Average triglyceride reduction (percent) | Best for | Potential side effects | |
|---|---|---|---|---|---|---|
| Drugs | ||||||
| Bile acid sequestrants | Up to 15 | 15-30 | 5 | Variable;may raise level | Lowering LDL | Gastrointestinal complaints |
| Fibrates | Up to 20 | variable to 15-20 decrease | 5-20 | 20-50 | Lowering triglycerides and raising HDL | Gastrointestinal complaints,increased risk of gallstones |
| Nicotinic acid | Up to 20 | 20-30 | 15-35 | 20-50 | All lipid abnormalities | Flushing, liver damage (in sustained-release form), gout, gastrointestinal complaints |
| Statins | Up to 40 | 20-60 | 5-15 | 10-40 | Lowering LDL;Zocor (sim-vastatin) is also approved for raising HDL | Liver damage,muscle weakness loss of libibo |
| Supplements | ||||||
| Chromium | Not significant | Not significant | Not significant | 17 | Lowering trgiyoerides | None |
| Fish oil | 12 | 17 | Not significant | 36 | Preventing LDL oxidation and improving heart function | Has blood-thinning properties; use with care if you'retaking other blood-thinners |
| Gulgulipid | 25 | 17 | Not significant | 18 | Lowering LDL and triglycerides | Gastrointestinal upsel, nausea,headache, diarrhea |
| Pantethine | 13.5 | 13.5 | 10 | 13-30 | Lowering LDL and tnglycerides and raising HDL | None |
| Psyllium | 7 | 7 | Not significant | Not significant | Lowering LDL | Bloating, gas,and abdominal diseamfort |
| Red yeast rice extract | 16-20 | 21-25 | Lass than 25 | 6-15 | Lowering LDL and triglycerides | Gastrointestinal discomfort, rash, headache |
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